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Search Results to Stavros Manolagas

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Manolagas, Stavros

One or more keywords matched the following items that are connected to Manolagas, Stavros

Item Type	Name
Academic Article	Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.
Academic Article	Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases.
Academic Article	Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts.
Academic Article	Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.
Academic Article	Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo.
Academic Article	Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens.
Academic Article	FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice.
Academic Article	Steap4 plays a critical role in osteoclastogenesis in vitro by regulating cellular iron/reactive oxygen species (ROS) levels and cAMP response element-binding protein (CREB) activation.
Academic Article	Osteoprotegerin prevents glucocorticoid-induced osteocyte apoptosis in mice.
Academic Article	Transduction of cell survival signals by connexin-43 hemichannels.
Academic Article	Suppression of autophagy in osteocytes mimics skeletal aging.
Academic Article	FOXOs attenuate bone formation by suppressing Wnt signaling.
Academic Article	The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone.
Concept	Cells, Cultured
Academic Article	FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation.
Academic Article	PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.
Academic Article	Oxidation-specific epitopes restrain bone formation.
Academic Article	Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors.

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Cells Cultured